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[[Image:1lua.png|left|200px]]


{{STRUCTURE_1lua|  PDB=1lua  |  SCENE=  }}
==Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylobacterium extorquens AM1 complexed with NADP==
 
<StructureSection load='1lua' size='340' side='right'caption='[[1lua]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylobacterium extorquens AM1 complexed with NADP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1lua]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylorubrum_extorquens_AM1 Methylorubrum extorquens AM1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LUA FirstGlance]. <br>
{{ABSTRACT_PUBMED_12176390}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lua OCA], [https://pdbe.org/1lua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lua RCSB], [https://www.ebi.ac.uk/pdbsum/1lua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lua ProSAT]</span></td></tr>
[[1lua]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylobacterium_extorquens Methylobacterium extorquens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LUA OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/MTDA_METEA MTDA_METEA] Catalyzes the dehydrogenation of methylene-H(4)MPT. Can also catalyze the reversible dehydrogenation of methylene-H(4)F with 20-fold lower catalytic efficiency.
<ref group="xtra">PMID:012176390</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Methylobacterium extorquens]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Demmer, U.]]
Check<jmol>
[[Category: Ermler, U.]]
  <jmolCheckbox>
[[Category: Grabarse, W.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lu/1lua_consurf.spt"</scriptWhenChecked>
[[Category: Hagemeier, C H.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Roth, A.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Vorholt, J A.]]
  </jmolCheckbox>
[[Category: Warkentin, E.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lua ConSurf].
[[Category: Alpha/beta twisted open sheet structure]]
<div style="clear:both"></div>
[[Category: Oxidoreductase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methylorubrum extorquens AM1]]
[[Category: Demmer U]]
[[Category: Ermler U]]
[[Category: Grabarse W]]
[[Category: Hagemeier CH]]
[[Category: Roth A]]
[[Category: Vorholt JA]]
[[Category: Warkentin E]]

Latest revision as of 13:26, 13 March 2024

Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylobacterium extorquens AM1 complexed with NADP

1lua, resolution 1.90Å

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