1nm8: Difference between revisions
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==Structure of Human Carnitine Acetyltransferase: Molecular Basis for Fatty Acyl Transfer== | |||
<StructureSection load='1nm8' size='340' side='right'caption='[[1nm8]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1nm8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NM8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nm8 OCA], [https://pdbe.org/1nm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nm8 RCSB], [https://www.ebi.ac.uk/pdbsum/1nm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nm8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CACP_HUMAN CACP_HUMAN] Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/1nm8_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nm8 ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[Carnitine acetyltransferase|Carnitine acetyltransferase]] | |||
__TOC__ | |||
</StructureSection> | |||
[[ | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Agbandje-McKenna | [[Category: Large Structures]] | ||
[[Category: Govindasamy | [[Category: Agbandje-McKenna M]] | ||
[[Category: Gu | [[Category: Govindasamy L]] | ||
[[Category: Kukar | [[Category: Gu Y]] | ||
[[Category: Lian | [[Category: Kukar T]] | ||
[[Category: McKenna | [[Category: Lian W]] | ||
[[Category: Wu | [[Category: McKenna R]] | ||
[[Category: Wu D]] | |||
Latest revision as of 07:57, 14 February 2024
Structure of Human Carnitine Acetyltransferase: Molecular Basis for Fatty Acyl Transfer
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