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[[Image:1mpt.png|left|200px]]


{{STRUCTURE_1mpt|  PDB=1mpt  |  SCENE=  }}
==CRYSTAL STRUCTURE OF A NEW ALKALINE SERINE PROTEASE (M-PROTEASE) FROM BACILLUS SP. KSM-K16==
 
<StructureSection load='1mpt' size='340' side='right'caption='[[1mpt]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
===CRYSTAL STRUCTURE OF A NEW ALKALINE SERINE PROTEASE (M-PROTEASE) FROM BACILLUS SP. KSM-K16===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1mpt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_clausii_KSM-K16 Alkalihalobacillus clausii KSM-K16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MPT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MPT FirstGlance]. <br>
{{ABSTRACT_PUBMED_15299321}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mpt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mpt OCA], [https://pdbe.org/1mpt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mpt RCSB], [https://www.ebi.ac.uk/pdbsum/1mpt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mpt ProSAT]</span></td></tr>
[[1mpt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_clausii Bacillus clausii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MPT OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/PRTM_ALKCK PRTM_ALKCK] Alkaline serine protease that cleaves various substrates, including N-succinyl-Ala-Ala-Pro-Phe-pNA, N-succinyl-Ala-Ala-Pro-MetpNA, oxidized insulin B chain, casein, hemoglobin and scleroproteins, such as keratin, alpha-keratin and elastin.<ref>PMID:7632397</ref>  
<ref group="xtra">PMID:015299321</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Bacillus clausii]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Subtilisin]]
Check<jmol>
[[Category: Ashida, T.]]
  <jmolCheckbox>
[[Category: Hatanaka, T.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mp/1mpt_consurf.spt"</scriptWhenChecked>
[[Category: Ito, S.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Kani, T.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Kobayashi, T.]]
  </jmolCheckbox>
[[Category: Suzuki, A.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mpt ConSurf].
[[Category: Yamane, T.]]
<div style="clear:both"></div>
[[Category: Yamashita, O.]]
== References ==
[[Category: Serine proteinase]]
<references/>
__TOC__
</StructureSection>
[[Category: Alkalihalobacillus clausii KSM-K16]]
[[Category: Large Structures]]
[[Category: Ashida T]]
[[Category: Hatanaka T]]
[[Category: Ito S]]
[[Category: Kani T]]
[[Category: Kobayashi T]]
[[Category: Suzuki A]]
[[Category: Yamane T]]
[[Category: Yamashita O]]