1m3u: Difference between revisions

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[[Image:1m3u.png|left|200px]]


{{STRUCTURE_1m3u|  PDB=1m3u  |  SCENE=  }}
==Crystal Structure of Ketopantoate Hydroxymethyltransferase complexed the Product Ketopantoate==
 
<StructureSection load='1m3u' size='340' side='right'caption='[[1m3u]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Crystal Structure of Ketopantoate Hydroxymethyltransferase complexed the Product Ketopantoate===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1m3u]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M3U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M3U FirstGlance]. <br>
{{ABSTRACT_PUBMED_12906829}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KPL:KETOPANTOATE'>KPL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m3u OCA], [https://pdbe.org/1m3u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m3u RCSB], [https://www.ebi.ac.uk/pdbsum/1m3u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m3u ProSAT]</span></td></tr>
[[1m3u]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M3U OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/PANB_ECOLI PANB_ECOLI] Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate.<ref>PMID:776976</ref>
<ref group="xtra">PMID:012906829</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: 3-methyl-2-oxobutanoate hydroxymethyltransferase]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m3/1m3u_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m3u ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Abell, C.]]
[[Category: Large Structures]]
[[Category: Blundell, T L.]]
[[Category: Abell C]]
[[Category: Delft, F von.]]
[[Category: Blundell TL]]
[[Category: Dhanaraj, V.]]
[[Category: Dhanaraj V]]
[[Category: Inoue, T.]]
[[Category: Inoue T]]
[[Category: Ottenhof, H H.]]
[[Category: Ottenhof HH]]
[[Category: Saldanha, S A.]]
[[Category: Saldanha SA]]
[[Category: Smith, A G.]]
[[Category: Smith AG]]
[[Category: Witty, M.]]
[[Category: Witty M]]
[[Category: Beta-alpha-barrel]]
[[Category: Von Delft F]]
[[Category: Decamer]]
[[Category: Ketopantoate]]
[[Category: Selenomethionine mad]]
[[Category: Tim-barrel]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/1m3u"