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[[Image:1m1f.png|left|200px]]


{{STRUCTURE_1m1f|  PDB=1m1f  |  SCENE=  }}
==Kid toxin protein from E.coli plasmid R1==
 
<StructureSection load='1m1f' size='340' side='right'caption='[[1m1f]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
===Kid toxin protein from E.coli plasmid R1===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1m1f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M1F FirstGlance]. <br>
{{ABSTRACT_PUBMED_12377128}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1f OCA], [https://pdbe.org/1m1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m1f RCSB], [https://www.ebi.ac.uk/pdbsum/1m1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m1f ProSAT]</span></td></tr>
[[1m1f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1F OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/PEMK_ECOLX PEMK_ECOLX] Toxic component of a type II toxin-antitoxin (TA) module. Probably functions as an endoribonuclease. Responsible for the stable maintenance of the plasmid during cell division by postsegregational killing of plasmid-less daughter cells. Neutralized by coexpression with cognate antitoxin PemI. Both PemI and PemK proteins bind to the promoter region of the pem operon to autoregulate their synthesis.<ref>PMID:2832364</ref> <ref>PMID:8455570</ref>  
<ref group="xtra">PMID:012377128</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m1/1m1f_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m1f ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Boelens, R.]]
[[Category: Large Structures]]
[[Category: Cueva-Mendez, G de la.]]
[[Category: Boelens R]]
[[Category: Diaz-Orejas, R.]]
[[Category: Diaz-Orejas R]]
[[Category: Giraldo, R.]]
[[Category: Giraldo R]]
[[Category: Hargreaves, D.]]
[[Category: Hargreaves D]]
[[Category: Rafferty, J B.]]
[[Category: Rafferty JB]]
[[Category: Sabariegos-Jareno, R.]]
[[Category: Sabariegos-Jareno R]]
[[Category: Santos-Sierra, S.]]
[[Category: Santos-Sierra S]]
[[Category: Ccdb]]
[[Category: De la Cueva-Mendez G]]
[[Category: Dna replication]]
[[Category: Mutational analysis]]
[[Category: Plasmid maintenance]]
[[Category: Post segregational killing]]
[[Category: Toxin]]
[[Category: Toxin-antitoxin]]
Retrieved from "https://proteopedia.org/1m1f"