1lu4: Difference between revisions

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[[Image:1lu4.png|left|200px]]


{{STRUCTURE_1lu4|  PDB=1lu4  |  SCENE=  }}
==1.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED MYCOBACTERIUM TUBERCULOSIS DISULFIDE OXIDOREDUCTASE HOMOLOGOUS TO E. COLI DSBE: IMPLICATIONS FOR FUNCTIONS==
 
<StructureSection load='1lu4' size='340' side='right'caption='[[1lu4]], [[Resolution|resolution]] 1.12&Aring;' scene=''>
===1.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED MYCOBACTERIUM TUBERCULOSIS DISULFIDE OXIDOREDUCTASE HOMOLOGOUS TO E. COLI DSBE: IMPLICATIONS FOR FUNCTIONS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1lu4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LU4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LU4 FirstGlance]. <br>
{{ABSTRACT_PUBMED_14597624}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lu4 OCA], [https://pdbe.org/1lu4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lu4 RCSB], [https://www.ebi.ac.uk/pdbsum/1lu4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lu4 ProSAT], [https://www.topsan.org/Proteins/TBSGC/1lu4 TOPSAN]</span></td></tr>
==About this Structure==
</table>
[[1lu4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LU4 OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/MPT53_MYCTU MPT53_MYCTU] Disulfide oxidoreductase that catalyzes the oxidation of reduced, unfolded secreted proteins to form disulfide bonds. Despite a weak homology to thioredoxin this cannot serve as a substrate for thioredoxin reductase.<ref>PMID:14597624</ref>  
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:014597624</ref><ref group="xtra">PMID:012906835</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lu/1lu4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lu4 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Apostol, M I.]]
[[Category: Apostol MI]]
[[Category: Bardwell, J.]]
[[Category: Bardwell J]]
[[Category: Eisenberg, D.]]
[[Category: Eisenberg D]]
[[Category: Gennaro, M.]]
[[Category: Gennaro M]]
[[Category: Gleiter, S.]]
[[Category: Gleiter S]]
[[Category: Goulding, C W.]]
[[Category: Goulding CW]]
[[Category: Parseghian, A.]]
[[Category: Parseghian A]]
[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: Oxidoreductase]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Tb structural genomics consortium]]
[[Category: Tbsgc]]
[[Category: Thioredoxin-like fold]]
Retrieved from "https://proteopedia.org/1lu4"