1ka9: Difference between revisions
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==Imidazole Glycerol Phosphate Synthase== | |||
<StructureSection load='1ka9' size='340' side='right'caption='[[1ka9]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1ka9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KA9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ka9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ka9 OCA], [https://pdbe.org/1ka9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ka9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ka9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ka9 ProSAT], [https://www.topsan.org/Proteins/RSGI/1ka9 TOPSAN]</span></td></tr> | |||
== | </table> | ||
[[1ka9]] is a 2 chain structure with sequence from [ | == Function == | ||
[https://www.uniprot.org/uniprot/HIS5_THET8 HIS5_THET8] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity).[HAMAP-Rule:MF_00278] | |||
== | == Evolutionary Conservation == | ||
< | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/1ka9_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ka9 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
[[Category: Hirotsu | [[Category: Hirotsu K]] | ||
[[Category: Miyahara | [[Category: Miyahara I]] | ||
[[Category: Omi | [[Category: Omi R]] | ||
Latest revision as of 13:25, 13 March 2024
Imidazole Glycerol Phosphate Synthase
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