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[[Image:1n5s.png|left|200px]]


{{STRUCTURE_1n5s| PDB=1n5s | SCENE= }}  
==Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Acetyl Dithranol==
<StructureSection load='1n5s' size='340' side='right'caption='[[1n5s]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1n5s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N5S FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PG:2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>1PG</scene>, <scene name='pdbligand=ADL:(1,8-DIHYDROXY-9-OXO-9,10-DIHYDRO-ANTHRACEN-2-YL)-ACETIC+ACID'>ADL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n5s OCA], [https://pdbe.org/1n5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n5s RCSB], [https://www.ebi.ac.uk/pdbsum/1n5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n5s ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q53908_STRCH Q53908_STRCH]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n5/1n5s_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n5s ConSurf].
<div style="clear:both"></div>


===Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Acetyl Dithranol===
==See Also==
 
*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
{{ABSTRACT_PUBMED_12514126}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[1n5s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N5S OCA].
[[Category: Federici L]]
 
[[Category: Kendrew SG]]
==Reference==
[[Category: Malatesta F]]
<ref group="xtra">PMID:012514126</ref><ref group="xtra">PMID:015103643</ref><references group="xtra"/>
[[Category: Marsh NG]]
[[Category: Streptomyces coelicolor]]
[[Category: Miele AE]]
[[Category: Federici, L.]]
[[Category: Savino C]]
[[Category: Kendrew, S G.]]
[[Category: Schimperna G]]
[[Category: Malatesta, F.]]
[[Category: Sciara G]]
[[Category: Marsh, N G.]]
[[Category: Vallone B]]
[[Category: Miele, A E.]]
[[Category: Savino, C.]]
[[Category: Schimperna, G.]]
[[Category: Sciara, G.]]
[[Category: Vallone, B.]]
[[Category: Acetyl dithranol]]
[[Category: Actinorhodin]]
[[Category: Aromatic polyketide]]
[[Category: Dihydrokalafungin]]
[[Category: Monooxygenase]]
[[Category: Oxidoreductase]]
[[Category: Streptomyces coelicolor]]

Latest revision as of 07:53, 14 February 2024

Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Acetyl Dithranol

1n5s, resolution 1.70Å

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