4i6w: Difference between revisions
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New page: '''Unreleased structure''' The entry 4i6w is ON HOLD Authors: Steussy, C.N., Stauffacher, C.V., Schmidt, T., Burgner II, J.W., Rodwell, V.W., Wrensford, L.V., Critchelow, C.J., Min, J. ... |
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==3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate== | |||
<StructureSection load='4i6w' size='340' side='right'caption='[[4i6w]], [[Resolution|resolution]] 1.66Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4i6w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I6W FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1CO:(3S)-3-HYDROXY-3-METHYL-5-SULFANYLPENTANOIC+ACID'>1CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i6w OCA], [https://pdbe.org/4i6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i6w RCSB], [https://www.ebi.ac.uk/pdbsum/4i6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i6w ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA. | |||
==See Also== | |||
*[[HMG-CoA Reductase 3D structures|HMG-CoA Reductase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pseudomonas mevalonii]] | |||
[[Category: Burgner II JW]] | |||
[[Category: Critchelow CJ]] | |||
[[Category: Min J]] | |||
[[Category: Rodwell VW]] | |||
[[Category: Schmidt T]] | |||
[[Category: Stauffacher CV]] | |||
[[Category: Steussy CN]] | |||
[[Category: Wrensford LV]] | |||
Latest revision as of 11:51, 1 March 2024
3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate
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