2l2x: Difference between revisions
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==Thiostrepton, oxidized at CA-CB bond of residue 9== | |||
<StructureSection load='2l2x' size='340' side='right'caption='[[2l2x]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2l2x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_azureus Streptomyces azureus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L2X FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | |||
== | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB9:(2Z)-2-AMINO-3-SULFANYLPROP-2-ENOIC+ACID'>BB9</scene>, <scene name='pdbligand=DBU:(2Z)-2-AMINOBUT-2-ENOIC+ACID'>DBU</scene>, <scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=MH6:3-HYDROXY-2-IMINOPROPANOIC+ACID'>MH6</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=QUA:8-HYDROXY-4-(1-HYDROXYETHYL)QUINOLINE-2-CARBOXYLIC+ACID'>QUA</scene>, <scene name='pdbligand=TS9:(2S,3S,4R)-2-AMINO-3,4-DIHYDROXY-3-METHYLPENTANOIC+ACID'>TS9</scene></td></tr> | ||
[[2l2x]] is a 1 chain structure with sequence from [ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l2x OCA], [https://pdbe.org/2l2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l2x RCSB], [https://www.ebi.ac.uk/pdbsum/2l2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l2x ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/THCL_STRAJ THCL_STRAJ] Has bacteriocidal activity. Inhibits bacterial protein biosynthesis by acting on the elongation factor Tu (EF-Tu) (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Streptomyces azureus]] | [[Category: Streptomyces azureus]] | ||
[[Category: Arndt | [[Category: Arndt H-D]] | ||
[[Category: Baumann | [[Category: Baumann S]] | ||
[[Category: Hiller | [[Category: Hiller F]] | ||
[[Category: Jonker | [[Category: Jonker HRA]] | ||
[[Category: Kirschner | [[Category: Kirschner KN]] | ||
[[Category: Schoof | [[Category: Schoof S]] | ||
[[Category: Schulte | [[Category: Schulte KW]] | ||
[[Category: Schwalbe | [[Category: Schwalbe H]] | ||
[[Category: Wolf | [[Category: Wolf A]] | ||
Latest revision as of 22:25, 26 March 2025
Thiostrepton, oxidized at CA-CB bond of residue 9
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