4f7z: Difference between revisions
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==Conformational dynamics of exchange protein directly activated by cAMP== | |||
<StructureSection load='4f7z' size='340' side='right'caption='[[4f7z]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4f7z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F7Z FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f7z OCA], [https://pdbe.org/4f7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f7z RCSB], [https://www.ebi.ac.uk/pdbsum/4f7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f7z ProSAT]</span></td></tr> | ||
[[4f7z]] is a 1 chain structure with sequence from [ | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/RPGF4_MOUSE RPGF4_MOUSE] Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2.<ref>PMID:11056535</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Cheng | [[Category: Cheng X]] | ||
[[Category: Liu | [[Category: Liu T]] | ||
[[Category: Mei | [[Category: Mei FC]] | ||
[[Category: Tsalkova | [[Category: Tsalkova TN]] | ||
[[Category: White | [[Category: White MA]] | ||
[[Category: Woods | [[Category: Woods VL]] | ||
Latest revision as of 15:18, 14 March 2024
Conformational dynamics of exchange protein directly activated by cAMP
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