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[[Image:1otg.png|left|200px]]


{{STRUCTURE_1otg|  PDB=1otg  |  SCENE=  }}
==5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE==
 
<StructureSection load='1otg' size='340' side='right'caption='[[1otg]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1otg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_C Escherichia coli C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTG FirstGlance]. <br>
{{ABSTRACT_PUBMED_8547259}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otg OCA], [https://pdbe.org/1otg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otg RCSB], [https://www.ebi.ac.uk/pdbsum/1otg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otg ProSAT]</span></td></tr>
[[1otg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTG OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/HPCD_ECOLX HPCD_ECOLX] Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET).
<ref group="xtra">PMID:008547259</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Escherichia coli]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Dauter, Z.]]
Check<jmol>
[[Category: Davies, G J.]]
  <jmolCheckbox>
[[Category: Dodson, E J.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/1otg_consurf.spt"</scriptWhenChecked>
[[Category: Roper, D I.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Subramanya, H S.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Wigley, D B.]]
  </jmolCheckbox>
[[Category: Wilson, K S.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1otg ConSurf].
[[Category: Hydroxymuconate]]
<div style="clear:both"></div>
[[Category: Isomerase]]
__TOC__
</StructureSection>
[[Category: Escherichia coli C]]
[[Category: Large Structures]]
[[Category: Dauter Z]]
[[Category: Davies GJ]]
[[Category: Dodson EJ]]
[[Category: Roper DI]]
[[Category: Subramanya HS]]
[[Category: Wigley DB]]
[[Category: Wilson KS]]

Latest revision as of 08:03, 14 February 2024

5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE

1otg, resolution 2.10Å

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