1oaa: Difference between revisions

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[[Image:1oaa.png|left|200px]]


{{STRUCTURE_1oaa|  PDB=1oaa  |  SCENE=  }}
==MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND OXALOACETATE==
 
<StructureSection load='1oaa' size='340' side='right'caption='[[1oaa]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
===MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND OXALOACETATE===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1oaa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OAA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OAA FirstGlance]. <br>
{{ABSTRACT_PUBMED_9405351}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oaa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oaa OCA], [https://pdbe.org/1oaa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oaa RCSB], [https://www.ebi.ac.uk/pdbsum/1oaa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oaa ProSAT]</span></td></tr>
[[1oaa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OAA OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/SPRE_MOUSE SPRE_MOUSE] Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
<ref group="xtra">PMID:009405351</ref><ref group="xtra">PMID:011917145</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oa/1oaa_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oaa ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Sepiapterin reductase]]
[[Category: Auerbach G]]
[[Category: Auerbach, G.]]
[[Category: Bacher A]]
[[Category: Bacher, A.]]
[[Category: Herrmann A]]
[[Category: Herrmann, A.]]
[[Category: Huber R]]
[[Category: Huber, R.]]
[[Category: Oxidoreductase]]
[[Category: Sepiapterin reductase]]
[[Category: Tetrahydrobiopterin]]
Retrieved from "https://proteopedia.org/1oaa"