4dt4: Difference between revisions

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[[Image:4dt4.png|left|200px]]


{{STRUCTURE_4dt4| PDB=4dt4 | SCENE= }}
==Crystal structure of the PPIase-chaperone SlpA with the chaperone binding site occupied by the linker of the purification tag==
<StructureSection load='4dt4' size='340' side='right'caption='[[4dt4]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4dt4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DT4 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dt4 OCA], [https://pdbe.org/4dt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dt4 RCSB], [https://www.ebi.ac.uk/pdbsum/4dt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dt4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FKBX_ECOLI FKBX_ECOLI] PPIases accelerate the folding of proteins. Substrate specificity investigated with 'Suc-Ala-Xaa-Pro-Phe-4-nitroanilide' where Xaa is the amino acid tested, was found to be Phe > Leu >> Ile > Lys = Ala > Trp > His >> Gln.


===Crystal structure of the PPIase-chaperone SlpA with the chaperone binding site occupied by the linker of the purification tag===
==See Also==
 
*[[Peptidyl-prolyl cis-trans isomerase 3D structures|Peptidyl-prolyl cis-trans isomerase 3D structures]]
{{ABSTRACT_PUBMED_22735173}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Escherichia coli K-12]]
[[4dt4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DT4 OCA].
[[Category: Large Structures]]
 
[[Category: Loew C]]
==Reference==
[[Category: Nordlund P]]
<ref group="xtra">PMID:022735173</ref><references group="xtra"/>
[[Category: Quistgaard EM]]
[[Category: Escherichia coli k-12]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Loew, C.]]
[[Category: Nordlund, P.]]
[[Category: Quistgaard, E M.]]
[[Category: Chaperone]]
[[Category: Fkbp domain]]
[[Category: If domain]]
[[Category: Isomerase]]
[[Category: Peptidyl-prolyl isomerase]]
[[Category: Ppiase]]