1pzu: Difference between revisions

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[[Image:1pzu.png|left|200px]]


{{STRUCTURE_1pzu|  PDB=1pzu  |  SCENE=  }}
==An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site==
 
<StructureSection load='1pzu' size='340' side='right'caption='[[1pzu]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
===An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1pzu]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PZU FirstGlance]. <br>
{{ABSTRACT_PUBMED_12949491}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pzu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pzu OCA], [https://pdbe.org/1pzu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pzu RCSB], [https://www.ebi.ac.uk/pdbsum/1pzu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pzu ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1pzu]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZU OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/NFAC2_HUMAN NFAC2_HUMAN] Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.<ref>PMID:21871017</ref>  
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:012949491</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pz/1pzu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pzu ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chen, L.]]
[[Category: Large Structures]]
[[Category: Harrison, S C.]]
[[Category: Chen L]]
[[Category: Hogan, P G.]]
[[Category: Harrison SC]]
[[Category: Jin, L.]]
[[Category: Hogan PG]]
[[Category: Macian, F.]]
[[Category: Jin L]]
[[Category: Rao, A.]]
[[Category: Macian F]]
[[Category: Sliz, P.]]
[[Category: Rao A]]
[[Category: Human il8 promoter]]
[[Category: Sliz P]]
[[Category: Nfat1-rhr homodimer]]
[[Category: Protein-dna complex]]
[[Category: Transcription factor]]
[[Category: Transcription-dna complex]]
Retrieved from "https://proteopedia.org/1pzu"