1r8d: Difference between revisions

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[[Image:1r8d.png|left|200px]]


{{STRUCTURE_1r8d| PDB=1r8d | SCENE= }}
==Crystal Structure of MtaN Bound to DNA==
<StructureSection load='1r8d' size='340' side='right'caption='[[1r8d]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1r8d]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R8D FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8d OCA], [https://pdbe.org/1r8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r8d RCSB], [https://www.ebi.ac.uk/pdbsum/1r8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r8d ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTA_BACSU MTA_BACSU] Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE.<ref>PMID:10200972</ref> <ref>PMID:18502870</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/1r8d_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r8d ConSurf].
<div style="clear:both"></div>


===Crystal Structure of MtaN Bound to DNA===
==See Also==
 
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
{{ABSTRACT_PUBMED_14985361}}
== References ==
 
<references/>
==About this Structure==
__TOC__
[[1r8d]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8D OCA].
</StructureSection>
 
==Reference==
<ref group="xtra">PMID:014985361</ref><references group="xtra"/>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Brennan, R G.]]
[[Category: Large Structures]]
[[Category: Newberry, K J.]]
[[Category: Brennan RG]]
[[Category: Protein-dna complex]]
[[Category: Newberry KJ]]
[[Category: Transcription-dna complex]]