1r62: Difference between revisions
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==Crystal structure of the C-terminal Domain of the Two-Component System Transmitter Protein NRII (NtrB)== | |||
<StructureSection load='1r62' size='340' side='right'caption='[[1r62]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1r62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R62 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r62 OCA], [https://pdbe.org/1r62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r62 RCSB], [https://www.ebi.ac.uk/pdbsum/1r62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r62 ProSAT]</span></td></tr> | |||
== | </table> | ||
[[1r62]] is a 1 chain structure with sequence from [ | == Function == | ||
[https://www.uniprot.org/uniprot/NTRB_ECOLI NTRB_ECOLI] NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of NtrC. In nitrogen limitation NtrB activates NtrC by phosphorylating it, while in nitrogen excess NtrC is dephosphorylated and consequently inactivated by NtrB. | |||
== | == Evolutionary Conservation == | ||
< | [[Image:Consurf_key_small.gif|200px|right]] | ||
[[ | Check<jmol> | ||
[[ | <jmolCheckbox> | ||
[[ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/1r62_consurf.spt"</scriptWhenChecked> | ||
[[ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[[Category: | <text>to colour the structure by Evolutionary Conservation</text> | ||
[[Category: | </jmolCheckbox> | ||
[[Category: | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r62 ConSurf]. | ||
[[Category: | <div style="clear:both"></div> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli K-12]] | ||
[[Category: Large Structures]] | |||
[[Category: Ninfa AJ]] | |||
[[Category: Peisach D]] | |||
[[Category: Pioszak AA]] | |||
[[Category: Song Y]] | |||
[[Category: Xu Z]] | |||
Latest revision as of 08:20, 14 February 2024
Crystal structure of the C-terminal Domain of the Two-Component System Transmitter Protein NRII (NtrB)
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