1xew: Difference between revisions
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==Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.== | |||
<StructureSection load='1xew' size='340' side='right'caption='[[1xew]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1xew]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XEW FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xew OCA], [https://pdbe.org/1xew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xew RCSB], [https://www.ebi.ac.uk/pdbsum/1xew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xew ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SMC_PYRFU SMC_PYRFU] Required for chromosome condensation and partitioning (By similarity). Binds single-stranded but not double-stranded DNA.[HAMAP-Rule:MF_01894] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xe/1xew_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xew ConSurf]. | |||
<div style="clear:both"></div> | |||
=== | ==See Also== | ||
*[[Condensin|Condensin]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
< | |||
[[Category: Pyrococcus furiosus]] | [[Category: Pyrococcus furiosus]] | ||
[[Category: Hopfner | [[Category: Hopfner K-P]] | ||
[[Category: Lammens | [[Category: Lammens A]] | ||
[[Category: Schele | [[Category: Schele A]] | ||
Latest revision as of 13:36, 13 March 2024
Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.
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