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[[Image:1wur.png|left|200px]]


{{STRUCTURE_1wur| PDB=1wur | SCENE= }}
==Structure of GTP cyclohydrolase I Complexed with 8-oxo-dGTP==
<StructureSection load='1wur' size='340' side='right'caption='[[1wur]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1wur]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WUR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8DG:8-OXO-2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>8DG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wur OCA], [https://pdbe.org/1wur PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wur RCSB], [https://www.ebi.ac.uk/pdbsum/1wur PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wur ProSAT], [https://www.topsan.org/Proteins/RSGI/1wur TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5SH52_THET8 Q5SH52_THET8]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wur_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wur ConSurf].
<div style="clear:both"></div>


===Structure of GTP cyclohydrolase I Complexed with 8-oxo-dGTP===
==See Also==
 
*[[Cyclohydrolase 3D structures|Cyclohydrolase 3D structures]]
{{ABSTRACT_PUBMED_16169877}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[1wur]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUR OCA].
 
==Reference==
<ref group="xtra">PMID:016169877</ref><references group="xtra"/>
[[Category: GTP cyclohydrolase I]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Kuramitsu, S.]]
[[Category: Kuramitsu S]]
[[Category: Masui, R.]]
[[Category: Masui R]]
[[Category: Nakagawa, N.]]
[[Category: Nakagawa N]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tanaka Y]]
[[Category: Tanaka, Y.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Beta barrel]]
[[Category: Hydrolase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Protein-inhibitor complex]]
[[Category: Pteridine]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Tetrahydrobiopterin]]

Latest revision as of 13:34, 13 March 2024

Structure of GTP cyclohydrolase I Complexed with 8-oxo-dGTP

1wur, resolution 1.82Å

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