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[[Image:1tt9.png|left|200px]]


{{STRUCTURE_1tt9|  PDB=1tt9  |  SCENE=  }}
==Structure of the bifunctional and Golgi associated formiminotransferase cyclodeaminase octamer==
 
<StructureSection load='1tt9' size='340' side='right'caption='[[1tt9]], [[Resolution|resolution]] 3.42&Aring;' scene=''>
===Structure of the bifunctional and Golgi associated formiminotransferase cyclodeaminase octamer===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1tt9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TT9 FirstGlance]. <br>
{{ABSTRACT_PUBMED_15272307}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.42&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tt9 OCA], [https://pdbe.org/1tt9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tt9 RCSB], [https://www.ebi.ac.uk/pdbsum/1tt9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tt9 ProSAT]</span></td></tr>
[[1tt9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TT9 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/FTCD_RAT FTCD_RAT] Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity).<ref>PMID:12160147</ref>  Binds and promotes bundling of vimentin filaments originating from the Golgi.<ref>PMID:12160147</ref>  
<ref group="xtra">PMID:015272307</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tt/1tt9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tt9 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Chen, D H.]]
[[Category: Chen DH]]
[[Category: Chiu, W.]]
[[Category: Chiu W]]
[[Category: Ludtke, S J.]]
[[Category: Ludtke SJ]]
[[Category: Mao, Y.]]
[[Category: Mao Y]]
[[Category: Quiocho, F A.]]
[[Category: Quiocho FA]]
[[Category: Vyas, M N.]]
[[Category: Vyas MN]]
[[Category: Vyas, N K.]]
[[Category: Vyas NK]]
[[Category: Hepatitis autoantigen]]
[[Category: Intermediate channeling]]
[[Category: Lyase]]
[[Category: Protein assembly]]
[[Category: Transferase]]
[[Category: Vimentin]]
Retrieved from "https://proteopedia.org/1tt9"