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[[Image:1tzf.png|left|200px]]


{{STRUCTURE_1tzf|  PDB=1tzf  |  SCENE=  }}
==X-ray Crystal Structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi==
 
<StructureSection load='1tzf' size='340' side='right'caption='[[1tzf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===X-ray Crystal Structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1tzf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhi_str._CT18 Salmonella enterica subsp. enterica serovar Typhi str. CT18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TZF FirstGlance]. <br>
{{ABSTRACT_PUBMED_15292268}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5G:[CYTIDINE-5-PHOSPHATE]-BETA-GLUCOSYL-PHOSPHORIC+ACID+ESTER'>C5G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tzf OCA], [https://pdbe.org/1tzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tzf RCSB], [https://www.ebi.ac.uk/pdbsum/1tzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tzf ProSAT]</span></td></tr>
[[1tzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZF OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/RFBF_SALTI RFBF_SALTI] Involved in the biosynthesis of the tyvelose, a 3,6-dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate. This enzyme can utilize either CTP or UTP as the nucleotide donor.<ref>PMID:15634670</ref>
<ref group="xtra">PMID:015292268</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Glucose-1-phosphate cytidylyltransferase]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Salmonella enterica subsp. enterica serovar typhi]]
Check<jmol>
[[Category: Holden, H M.]]
  <jmolCheckbox>
[[Category: Koropatkin, N M.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tz/1tzf_consurf.spt"</scriptWhenChecked>
[[Category: Mixed alpha/beta fold]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Nucleotidyltransferase]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Transferase]]
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tzf ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhi str. CT18]]
[[Category: Holden HM]]
[[Category: Koropatkin NM]]

Latest revision as of 08:43, 14 February 2024

X-ray Crystal Structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi

1tzf, resolution 2.10Å

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