1t90: Difference between revisions
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==Crystal structure of methylmalonate semialdehyde dehydrogenase from Bacillus subtilis== | |||
<StructureSection load='1t90' size='340' side='right'caption='[[1t90]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1t90]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T90 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
== | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | ||
[[1t90]] is a 4 chain structure with sequence from [ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t90 OCA], [https://pdbe.org/1t90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t90 RCSB], [https://www.ebi.ac.uk/pdbsum/1t90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t90 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IOLA_BACSU IOLA_BACSU] Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.<ref>PMID:16332250</ref> <ref>PMID:18310071</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t9/1t90_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t90 ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Aubry | [[Category: Large Structures]] | ||
[[Category: Branlant | [[Category: Aubry A]] | ||
[[Category: Corbier | [[Category: Branlant G]] | ||
[[Category: Didierjean | [[Category: Corbier C]] | ||
[[Category: Dubourg | [[Category: Didierjean C]] | ||
[[Category: Stines-Chaumeil | [[Category: Dubourg H]] | ||
[[Category: Talfournier | [[Category: Stines-Chaumeil C]] | ||
[[Category: Talfournier F]] | |||