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[[Image:1to0.png|left|200px]]


{{STRUCTURE_1to0|  PDB=1to0  |  SCENE=  }}
==X-ray structure of Northeast Structural Genomics target protein sr145 from Bacillus subtilis==
 
<StructureSection load='1to0' size='340' side='right'caption='[[1to0]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===X-ray structure of Northeast Structural Genomics target protein sr145 from Bacillus subtilis===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1to0]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TO0 FirstGlance]. <br>
{{ABSTRACT_PUBMED_016460560}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1to0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1to0 OCA], [https://pdbe.org/1to0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1to0 RCSB], [https://www.ebi.ac.uk/pdbsum/1to0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1to0 ProSAT], [https://www.topsan.org/Proteins/NESGC/1to0 TOPSAN]</span></td></tr>
[[1to0]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TO0 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/RLMH_BACSU RLMH_BACSU] Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.[HAMAP-Rule:MF_00658]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/to/1to0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1to0 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Acton, T.]]
[[Category: Large Structures]]
[[Category: Edstrom, W.]]
[[Category: Acton T]]
[[Category: Hunt, J F.]]
[[Category: Edstrom W]]
[[Category: Kuzin, A P.]]
[[Category: Hunt JF]]
[[Category: Ma, L C.]]
[[Category: Kuzin AP]]
[[Category: Montelione, G T.]]
[[Category: Ma L-C]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Montelione GT]]
[[Category: Shastry, R.]]
[[Category: Shastry R]]
[[Category: Tong, L.]]
[[Category: Tong L]]
[[Category: Vorobiev, S M.]]
[[Category: Vorobiev SM]]
[[Category: Xiao, R.]]
[[Category: Xiao R]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Unknown function]]