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[[Image:2bpa.png|left|200px]]


{{STRUCTURE_2bpa|  PDB=2bpa  |  SCENE=  }}
==ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS==
 
<StructureSection load='2bpa' size='340' side='right'caption='[[2bpa]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
===ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2bpa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_phiX174 Escherichia virus phiX174]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BPA FirstGlance]. <br>
{{ABSTRACT_PUBMED_1370343}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bpa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpa OCA], [https://pdbe.org/2bpa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bpa RCSB], [https://www.ebi.ac.uk/pdbsum/2bpa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bpa ProSAT]</span></td></tr>
==About this Structure==
</table>
[[2bpa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_phix174 Enterobacteria phage phix174]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPA OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/CAPSD_BPPHS CAPSD_BPPHS] Assembles to form an icosahedral capsid with a T=1 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins F (PubMed:11991963, PubMed:1370343, PubMed:8158636). Upon virus binding to host cell, one of the spikes dissociates from the capsid and the virus interacts with LPS through the exposed EF loops on the F proteins (PubMed:29229840). After the genome had been ejected, the channel formed by the F proteins at the unique fivefold axis remains open (PubMed:29229840).<ref>PMID:11991963</ref> <ref>PMID:1370343</ref> <ref>PMID:29229840</ref> <ref>PMID:8158636</ref>  
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:001370343</ref><ref group="xtra">PMID:012215419</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Enterobacteria phage phix174]]
Check<jmol>
[[Category: Baker, T S.]]
  <jmolCheckbox>
[[Category: Ilag, L L.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/2bpa_consurf.spt"</scriptWhenChecked>
[[Category: Incardona, N L.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Krishnaswamy, S.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: McKenna, R.]]
  </jmolCheckbox>
[[Category: Olson, N H.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bpa ConSurf].
[[Category: Rossmann, M G.]]
<div style="clear:both"></div>
[[Category: Willingmann, P.]]
== References ==
[[Category: Xia, D.]]
<references/>
[[Category: Icosahedral virus]]
__TOC__
[[Category: Protein-dna complex]]
</StructureSection>
[[Category: Single strand]]
[[Category: Escherichia virus phiX174]]
[[Category: Virus-dna complex]]
[[Category: Large Structures]]
[[Category: Baker TS]]
[[Category: Ilag LL]]
[[Category: Incardona NL]]
[[Category: Krishnaswamy S]]
[[Category: McKenna R]]
[[Category: Olson NH]]
[[Category: Rossmann MG]]
[[Category: Willingmann P]]
[[Category: Xia D]]
Retrieved from "https://proteopedia.org/2bpa"