2egy: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2egy.png|left|200px]]


{{STRUCTURE_2egy| PDB=2egy | SCENE= }}
==Crystal structure of LysN, alpha-aminoadipate aminotransferase (substrate free form), from Thermus thermophilus HB27==
<StructureSection load='2egy' size='340' side='right'caption='[[2egy]], [[Resolution|resolution]] 2.67&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2egy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EGY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.67&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2egy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2egy OCA], [https://pdbe.org/2egy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2egy RCSB], [https://www.ebi.ac.uk/pdbsum/2egy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2egy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LYSN_THET2 LYSN_THET2] Catalyzes the transfer of an amino group between 2-oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also contributes in the biosynthesis of other amino acids such as leucine.<ref>PMID:15256574</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/2egy_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2egy ConSurf].
<div style="clear:both"></div>


===Crystal structure of LysN, alpha-aminoadipate aminotransferase (substrate free form), from Thermus thermophilus HB27===
==See Also==
 
*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
{{ABSTRACT_PUBMED_15256574}}
== References ==
 
<references/>
==About this Structure==
__TOC__
[[2egy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGY OCA].
</StructureSection>
 
[[Category: Large Structures]]
==Reference==
[[Category: Thermus thermophilus HB27]]
<ref group="xtra">PMID:015256574</ref><references group="xtra"/>
[[Category: Fushinobu S]]
[[Category: 2-aminoadipate transaminase]]
[[Category: Kuzuyama T]]
[[Category: Thermus thermophilus]]
[[Category: Miyagawa T]]
[[Category: Fushinobu, S.]]
[[Category: Miyazaki T]]
[[Category: Kuzuyama, T.]]
[[Category: Nishiyama M]]
[[Category: Miyagawa, T.]]
[[Category: Tomita T]]
[[Category: Miyazaki, T.]]
[[Category: Nishiyama, M.]]
[[Category: Tomita, T.]]
[[Category: Alpha-aminoadipate aminotransferase]]
[[Category: Substrate specificity]]
[[Category: Thermus thermophilus]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/2egy"