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[[Image:1v5v.jpg|left|200px]]<br /><applet load="1v5v" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1v5v, resolution 1.50&Aring;" />
'''Crystal Structure of a Component of Glycine Cleavage System: T-protein from Pyrococcus horikoshii OT3 at 1.5 A Resolution'''<br />


==About this Structure==
==Crystal Structure of a Component of Glycine Cleavage System: T-protein from Pyrococcus horikoshii OT3 at 1.5 A Resolution==
1V5V is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with <scene name='pdbligand=GOL:'>GOL</scene> and <scene name='pdbligand=PEG:'>PEG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aminomethyltransferase Aminomethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.10 2.1.2.10] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5V OCA].  
<StructureSection load='1v5v' size='340' side='right'caption='[[1v5v]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1v5v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5V FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5v OCA], [https://pdbe.org/1v5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5v RCSB], [https://www.ebi.ac.uk/pdbsum/1v5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5v ProSAT], [https://www.topsan.org/Proteins/RSGI/1v5v TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GCST_PYRHO GCST_PYRHO] The glycine cleavage system catalyzes the degradation of glycine (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5v_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5v ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
Crystal structure of a component of glycine cleavage system: T-protein from Pyrococcus horikoshii OT3 at 1.5 A resolution., Lokanath NK, Kuroishi C, Okazaki N, Kunishima N, Proteins. 2005 Feb 15;58(3):769-73. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15609340 15609340]
*[[Aminomethyltransferase 3D structures|Aminomethyltransferase 3D structures]]
[[Category: Aminomethyltransferase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
[[Category: Single protein]]
[[Category: Kunishima N]]
[[Category: Kunishima, N.]]
[[Category: Lokanath NK]]
[[Category: Lokanath, N K.]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: GOL]]
[[Category: PEG]]
[[Category: aminomethyl transferase]]
[[Category: glycine-cleavage sytem]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
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Retrieved from "https://proteopedia.org/1v5v"