2d6f: Difference between revisions

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[[Image:2d6f.png|left|200px]]


{{STRUCTURE_2d6f| PDB=2d6f | SCENE= }}
==Crystal structure of Glu-tRNA(Gln) amidotransferase in the complex with tRNA(Gln)==
<StructureSection load='2d6f' size='340' side='right'caption='[[2d6f]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2d6f]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D6F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D6F FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d6f OCA], [https://pdbe.org/2d6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d6f RCSB], [https://www.ebi.ac.uk/pdbsum/2d6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d6f ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GATD_METTH GATD_METTH] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d6/2d6f_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d6f ConSurf].
<div style="clear:both"></div>


===Crystal structure of Glu-tRNA(Gln) amidotransferase in the complex with tRNA(Gln)===
==See Also==
 
*[[Glutamyl-tRNA(Gln) amidotransferase|Glutamyl-tRNA(Gln) amidotransferase]]
{{ABSTRACT_PUBMED_16809540}}
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
 
__TOC__
==About this Structure==
</StructureSection>
[[2d6f]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D6F OCA].
[[Category: Large Structures]]
 
==Reference==
<ref group="xtra">PMID:016809540</ref><references group="xtra"/>
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Nureki, O.]]
[[Category: Nureki O]]
[[Category: Ligase]]
[[Category: Ligase-rna complex]]
[[Category: Rna]]
Retrieved from "https://proteopedia.org/2d6f"