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[[Image:1vci.gif|left|200px]]<br /><applet load="1vci" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1vci, resolution 2.9&Aring;" />
'''Crystal structure of the ATP-binding cassette of multisugar transporter from Pyrococcus horikoshii OT3 complexed with ATP'''<br />


==About this Structure==
==Crystal structure of the ATP-binding cassette of multisugar transporter from Pyrococcus horikoshii OT3 complexed with ATP==
1VCI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with <scene name='pdbligand=ATP:'>ATP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCI OCA].  
<StructureSection load='1vci' size='340' side='right'caption='[[1vci]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1vci]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VCI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vci OCA], [https://pdbe.org/1vci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vci RCSB], [https://www.ebi.ac.uk/pdbsum/1vci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vci ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O57758_PYRHO O57758_PYRHO]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vc/1vci_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vci ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
Crystal structure of the ATP-binding cassette of multisugar transporter from Pyrococcus horikoshii OT3., Ose T, Fujie T, Yao M, Watanabe N, Tanaka I, Proteins. 2004 Nov 15;57(3):635-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15382245 15382245]
*[[ABC transporter 3D structures|ABC transporter 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
[[Category: Single protein]]
[[Category: Fujie T]]
[[Category: Fujie, T.]]
[[Category: Ose T]]
[[Category: Ose, T.]]
[[Category: Tanaka I]]
[[Category: Tanaka, I.]]
[[Category: Watanabe N]]
[[Category: Watanabe, N.]]
[[Category: Yao M]]
[[Category: Yao, M.]]
[[Category: ATP]]
[[Category: abc transporter]]
[[Category: atpase]]
[[Category: sugar-binding]]
 
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