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[[Image:2afv.png|left|200px]]


{{STRUCTURE_2afv|  PDB=2afv  |  SCENE=  }}
==The Crystal Structure of Putative Precorrin Isomerase CbiC in Cobalamin Biosynthesis==
 
<StructureSection load='2afv' size='340' side='right'caption='[[2afv]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
===The Crystal Structure of Putative Precorrin Isomerase CbiC in Cobalamin Biosynthesis===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2afv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leptospira_interrogans Leptospira interrogans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AFV FirstGlance]. <br>
{{ABSTRACT_PUBMED_16427313}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2afv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2afv OCA], [https://pdbe.org/2afv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2afv RCSB], [https://www.ebi.ac.uk/pdbsum/2afv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2afv ProSAT]</span></td></tr>
[[2afv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leptospira_interrogans Leptospira interrogans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AFV OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/CBIC_LEPIN CBIC_LEPIN] Catalyzes the conversion of cobalt-precorrin-8 to cobyrinate.
<ref group="xtra">PMID:016427313</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/af/2afv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2afv ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Leptospira interrogans]]
[[Category: Leptospira interrogans]]
[[Category: Precorrin-8X methylmutase]]
[[Category: Wei Z]]
[[Category: Wei, Z.]]
[[Category: Xue Y]]
[[Category: Xue, Y.]]
[[Category: Isomerase]]

Latest revision as of 13:41, 13 March 2024

The Crystal Structure of Putative Precorrin Isomerase CbiC in Cobalamin Biosynthesis

2afv, resolution 3.00Å

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