1vgk: Difference between revisions

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[[Image:1vgk.gif|left|200px]]<br /><applet load="1vgk" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1vgk, resolution 2.06&Aring;" />
'''The crystal structure of class I Major histocompatibility complex, H-2Kd at 2.0 A resolution'''<br />


==Disease==
==The crystal structure of class I Major histocompatibility complex, H-2Kd at 2.0 A resolution==
Known disease associated with this structure: Hypoproteinemia, hypercatabolic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=109700 109700]]
<StructureSection load='1vgk' size='340' side='right'caption='[[1vgk]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1vgk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VGK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VGK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vgk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vgk OCA], [https://pdbe.org/1vgk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vgk RCSB], [https://www.ebi.ac.uk/pdbsum/1vgk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vgk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HA1D_MOUSE HA1D_MOUSE] Involved in the presentation of foreign antigens to the immune system.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vg/1vgk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vgk ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
1VGK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VGK OCA].
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
*[[MHC 3D structures|MHC 3D structures]]
*[[MHC I 3D structures|MHC I 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Gao GF]]
[[Category: Gao, G F.]]
[[Category: Liu Y]]
[[Category: Liu, Y.]]
[[Category: Rao Z]]
[[Category: Rao, Z.]]
[[Category: Tien P]]
[[Category: Tien, P.]]
[[Category: Xu Y]]
[[Category: Xu, Y.]]
[[Category: Zhou M]]
[[Category: Zhou, M.]]
[[Category: class i]]
[[Category: crystal structure]]
[[Category: h-2kd]]
[[Category: mhc]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:35:02 2008''
Retrieved from "https://proteopedia.org/1vgk"