2d9c: Difference between revisions

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[[Image:2d9c.png|left|200px]]


{{STRUCTURE_2d9c|  PDB=2d9c  |  SCENE=  }}
==Solution structure of the first ig-like domain of signal-regulatory protein beta-1 (SIRP-beta-1)==
 
<StructureSection load='2d9c' size='340' side='right'caption='[[2d9c]]' scene=''>
===Solution structure of the first ig-like domain of signal-regulatory protein beta-1 (SIRP-beta-1)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2d9c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D9C FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d9c OCA], [https://pdbe.org/2d9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d9c RCSB], [https://www.ebi.ac.uk/pdbsum/2d9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d9c ProSAT], [https://www.topsan.org/Proteins/RSGI/2d9c TOPSAN]</span></td></tr>
[[2d9c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D9C OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SIRB1_HUMAN SIRB1_HUMAN] Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d9/2d9c_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d9c ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hayashi, F.]]
[[Category: Large Structures]]
[[Category: Nagashima, K.]]
[[Category: Hayashi F]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Nagashima K]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: Yoshida, M.]]
[[Category: Yoshida M]]
[[Category: Beta-sandwich]]
[[Category: Cd172b antigen]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Protein binding]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Sirp-beta-1]]
[[Category: Structural genomic]]
Retrieved from "https://proteopedia.org/2d9c"