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[[Image:2fvu.png|left|200px]]


{{STRUCTURE_2fvu|  PDB=2fvu  |  SCENE=  }}
==Structure of the yeast Sir3 BAH domain==
 
<StructureSection load='2fvu' size='340' side='right'caption='[[2fvu]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===Structure of the yeast Sir3 BAH domain===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2fvu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FVU FirstGlance]. <br>
{{ABSTRACT_PUBMED_16581798}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fvu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fvu OCA], [https://pdbe.org/2fvu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fvu RCSB], [https://www.ebi.ac.uk/pdbsum/2fvu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fvu ProSAT]</span></td></tr>
==About this Structure==
</table>
[[2fvu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVU OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/SIR3_YEAST SIR3_YEAST] The proteins SIR1 through SIR4 are required for transcriptional repression of the silent mating type loci, HML and HMR. The proteins SIR2 through SIR4 repress mulitple loci by modulating chromatin structure. Involves the compaction of chromatin fiber into a more condensed form.
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:016581798</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/2fvu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fvu ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Xu, R M.]]
[[Category: Xu RM]]
[[Category: Mainly beta]]
[[Category: Transcription]]
Retrieved from "https://proteopedia.org/2fvu"