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[[Image:2pb0.png|left|200px]]


{{STRUCTURE_2pb0|  PDB=2pb0  |  SCENE=  }}
==Structure of biosynthetic N-acetylornithine aminotransferase from Salmonella typhimurium: studies on substrate specificity and inhibitor binding==
 
<StructureSection load='2pb0' size='340' side='right'caption='[[2pb0]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
===Structure of biosynthetic N-acetylornithine aminotransferase from Salmonella typhimurium: studies on substrate specificity and inhibitor binding===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2pb0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PB0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PB0 FirstGlance]. <br>
{{ABSTRACT_PUBMED_17680699}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pb0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pb0 OCA], [https://pdbe.org/2pb0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pb0 RCSB], [https://www.ebi.ac.uk/pdbsum/2pb0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pb0 ProSAT]</span></td></tr>
[[2pb0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PB0 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/ARGD_SALTY ARGD_SALTY] Involved in both the arginine and lysine biosynthetic pathways (By similarity).[HAMAP-Rule:MF_01107]
<ref group="xtra">PMID:017680699</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Murthy, M R.N.]]
Check<jmol>
[[Category: Prasuna, P Ratna.]]
  <jmolCheckbox>
[[Category: Rajaram, V.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/2pb0_consurf.spt"</scriptWhenChecked>
[[Category: Savithri, H S.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Argd]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Arginine metabolism]]
  </jmolCheckbox>
[[Category: Gabaculine]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pb0 ConSurf].
[[Category: Lysine biosynthesis]]
<div style="clear:both"></div>
[[Category: Pyridoxal-5'-phosphate]]
__TOC__
[[Category: Transferase]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Murthy MRN]]
[[Category: Rajaram V]]
[[Category: Ratna Prasuna P]]
[[Category: Savithri HS]]

Latest revision as of 06:30, 3 April 2024

Structure of biosynthetic N-acetylornithine aminotransferase from Salmonella typhimurium: studies on substrate specificity and inhibitor binding

2pb0, resolution 1.96Å

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