2pbr: Difference between revisions

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[[Image:2pbr.png|left|200px]]


{{STRUCTURE_2pbr| PDB=2pbr | SCENE= }}
==Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5==
<StructureSection load='2pbr' size='340' side='right'caption='[[2pbr]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2pbr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PBR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbr OCA], [https://pdbe.org/2pbr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pbr RCSB], [https://www.ebi.ac.uk/pdbsum/2pbr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pbr ProSAT], [https://www.topsan.org/Proteins/RSGI/2pbr TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KTHY_AQUAE KTHY_AQUAE] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/2pbr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pbr ConSurf].
<div style="clear:both"></div>


===Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5===
==See Also==
 
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[2pbr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBR OCA].
[[Category: Aquifex aeolicus VF5]]
[[Category: Aquifex aeolicus]]
[[Category: Large Structures]]
[[Category: DTMP kinase]]
[[Category: Ebihara A]]
[[Category: Ebihara, A.]]
[[Category: Jeyakanthan J]]
[[Category: Jeyakanthan, J.]]
[[Category: Kanaujia SP]]
[[Category: Kanaujia, S P.]]
[[Category: Kuramitsu S]]
[[Category: Kuramitsu, S.]]
[[Category: Nakagawa N]]
[[Category: Nakagawa, N.]]
[[Category: Sekar K]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Shinkai A]]
[[Category: Ranjani, C Vasuki.]]
[[Category: Shiro Y]]
[[Category: Sekar, K.]]
[[Category: Vasuki Ranjani C]]
[[Category: Shinkai, A.]]
[[Category: Yokoyama S]]
[[Category: Shiro, Y.]]
[[Category: Yokoyama, S.]]
[[Category: Atp-binding]]
[[Category: Kinase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nucleotide biosynthesis]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Tmp-binding]]
[[Category: Transferase]]

Latest revision as of 08:59, 25 October 2023

Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5

2pbr, resolution 1.96Å

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