2kvf: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "2kvf" [edit=sysop:move=sysop] |
No edit summary |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Structure of the three-Cys2His2 domain of mouse testis zinc finger protein== | |||
<StructureSection load='2kvf' size='340' side='right'caption='[[2kvf]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2kvf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KVF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KVF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
== | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[2kvf]] is a 1 chain structure with sequence from [ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kvf OCA], [https://pdbe.org/2kvf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kvf RCSB], [https://www.ebi.ac.uk/pdbsum/2kvf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kvf ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ZBT32_MOUSE ZBT32_MOUSE] DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor (By similarity). Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.<ref>PMID:11279021</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Chen | [[Category: Chen C]] | ||
[[Category: Chou | [[Category: Chou C-C]] | ||
[[Category: Lou | [[Category: Lou Y-C]] | ||
Latest revision as of 06:49, 1 May 2024
Structure of the three-Cys2His2 domain of mouse testis zinc finger protein
| ||||||||||||
