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[[Image:2j0x.png|left|200px]]


{{STRUCTURE_2j0x|  PDB=2j0x  |  SCENE=  }}
==CRYSTAL STRUCTURE OF E. COLI ASPARTOKINASE III IN COMPLEX WITH LYSINE AND ASPARTATE (T-STATE)==
 
<StructureSection load='2j0x' size='340' side='right'caption='[[2j0x]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
===CRYSTAL STRUCTURE OF E. COLI ASPARTOKINASE III IN COMPLEX WITH LYSINE AND ASPARTATE (T-STATE)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2j0x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J0X FirstGlance]. <br>
{{ABSTRACT_PUBMED_16905770}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j0x OCA], [https://pdbe.org/2j0x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j0x RCSB], [https://www.ebi.ac.uk/pdbsum/2j0x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j0x ProSAT]</span></td></tr>
[[2j0x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0X OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/AK3_ECOLI AK3_ECOLI]
<ref group="xtra">PMID:016905770</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Aspartate kinase]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j0/2j0x_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j0x ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Hawkins, A R.]]
[[Category: Large Structures]]
[[Category: Kotaka, M.]]
[[Category: Hawkins AR]]
[[Category: Lockyer, M.]]
[[Category: Kotaka M]]
[[Category: Ren, J.]]
[[Category: Lockyer M]]
[[Category: Stammers, D K.]]
[[Category: Ren J]]
[[Category: Act domain]]
[[Category: Stammers DK]]
[[Category: Allosteric regulation]]
[[Category: Amino acid biosynthesis]]
[[Category: Amino-acid biosynthesis]]
[[Category: Aspartate pathway]]
[[Category: Aspartokinase]]
[[Category: Feedback inhibition]]
[[Category: Kinase]]
[[Category: Lysine]]
[[Category: Lysine biosynthesis]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/2j0x"