1w39: Difference between revisions

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[[Image:1w39.gif|left|200px]]<br /><applet load="1w39" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1w39, resolution 3.75&Aring;" />
'''CRYSTAL STRUCTURE OF AN ARTIFICIAL TOP COMPONENT OF TURNIP YELLOW MOSAIC VIRUS'''<br />


==Overview==
==Crystal structure of an artificial top component of turnip yellow mosaic virus==
<StructureSection load='1w39' size='340' side='right'caption='[[1w39]], [[Resolution|resolution]] 3.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1w39]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W39 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.75&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w39 OCA], [https://pdbe.org/1w39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w39 RCSB], [https://www.ebi.ac.uk/pdbsum/1w39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w39 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COAT_TYMV COAT_TYMV]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w3/1w39_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w39 ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Empty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection.
Empty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection.


==About this Structure==
Crystal structure of an empty capsid of turnip yellow mosaic virus.,van Roon AM, Bink HH, Plaisier JR, Pleij CW, Abrahams JP, Pannu NS J Mol Biol. 2004 Aug 27;341(5):1205-14. PMID:15321716<ref>PMID:15321716</ref>
1W39 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W39 OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
Crystal structure of an empty capsid of turnip yellow mosaic virus., van Roon AM, Bink HH, Plaisier JR, Pleij CW, Abrahams JP, Pannu NS, J Mol Biol. 2004 Aug 27;341(5):1205-14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15321716 15321716]
</div>
[[Category: Single protein]]
<div class="pdbe-citations 1w39" style="background-color:#fffaf0;"></div>
 
==See Also==
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Turnip yellow mosaic virus]]
[[Category: Turnip yellow mosaic virus]]
[[Category: Abrahams, J P.]]
[[Category: Abrahams JP]]
[[Category: Bink, H H.J.]]
[[Category: Bink HHJ]]
[[Category: Pannu, N S.]]
[[Category: Pannu NS]]
[[Category: Plaisier, J R.]]
[[Category: Plaisier JR]]
[[Category: Pleij, C W.A.]]
[[Category: Pleij CWA]]
[[Category: Roon, A M.M Van.]]
[[Category: Van Roon AMM]]
[[Category: artificial top component]]
[[Category: capsid protein]]
[[Category: crystallography]]
[[Category: icosahedral virus]]
[[Category: tymv]]
[[Category: virus]]
[[Category: virus/viral protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:40:00 2008''
Retrieved from "https://proteopedia.org/1w39"