2k7n: Difference between revisions

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[[Image:2k7n.png|left|200px]]


{{STRUCTURE_2k7n|  PDB=2k7n  |  SCENE=  }}
==Solution structure of the PPIL1 bound to a fragment of SKIP==
 
<StructureSection load='2k7n' size='340' side='right'caption='[[2k7n]]' scene=''>
===Solution structure of the PPIL1 bound to a fragment of SKIP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2k7n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K7N FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k7n OCA], [https://pdbe.org/2k7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k7n RCSB], [https://www.ebi.ac.uk/pdbsum/2k7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k7n ProSAT]</span></td></tr>
[[2k7n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K7N OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/PPIL1_HUMAN PPIL1_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.<ref>PMID:16595688</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k7/2k7n_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k7n ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Large Structures]]
[[Category: Shi, Y.]]
[[Category: Shi Y]]
[[Category: Wang, X.]]
[[Category: Wang X]]
[[Category: Wu, J.]]
[[Category: Wu J]]
[[Category: Beta barrel]]
[[Category: Disorder-order transition]]
[[Category: Hook-like]]
[[Category: Isomerase]]
[[Category: Mrna processing]]
[[Category: Mrna splicing]]
[[Category: Rotamase]]
[[Category: Spliceosome]]
Retrieved from "https://proteopedia.org/2k7n"