2i6t: Difference between revisions

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[[Image:2i6t.png|left|200px]]


{{STRUCTURE_2i6t|  PDB=2i6t  |  SCENE=  }}
==Orthorhombic Structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A==
 
<StructureSection load='2i6t' size='340' side='right'caption='[[2i6t]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===Orthorhombic Structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2i6t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I6T FirstGlance]. <br>
{{ABSTRACT_PUBMED_12427560}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i6t OCA], [https://pdbe.org/2i6t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i6t RCSB], [https://www.ebi.ac.uk/pdbsum/2i6t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i6t ProSAT]</span></td></tr>
[[2i6t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6T OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/UEVLD_HUMAN UEVLD_HUMAN] Possible negative regulator of polyubiquitination.<ref>PMID:12427560</ref>  
<ref group="xtra">PMID:012427560</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/2i6t_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i6t ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Avvakumov, G V.]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev, A.]]
[[Category: Avvakumov GV]]
[[Category: Butler-Cole, C.]]
[[Category: Bochkarev A]]
[[Category: Dhe-Paganon, S.]]
[[Category: Butler-Cole C]]
[[Category: Edwards, A M.]]
[[Category: Dhe-Paganon S]]
[[Category: Finerty, P J.]]
[[Category: Edwards AM]]
[[Category: Newman, E M.]]
[[Category: Finerty Jr PJ]]
[[Category: Sundstrom, M.]]
[[Category: Newman EM]]
[[Category: Tempel, W.]]
[[Category: Sundstrom M]]
[[Category: Walker, J R.]]
[[Category: Tempel W]]
[[Category: Weigelt, J.]]
[[Category: Walker JR]]
[[Category: Xue, S.]]
[[Category: Weigelt J]]
[[Category: L-lactate dehydrogenase]]
[[Category: Xue S]]
[[Category: Oxidoreductase]]
[[Category: Ubiquitin-protein ligase]]
[[Category: Unknown function]]
Retrieved from "https://proteopedia.org/2i6t"