2fr0: Difference between revisions

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[[Image:2fr0.png|left|200px]]


{{STRUCTURE_2fr0|  PDB=2fr0  |  SCENE=  }}
==The first ketoreductase of the erythromycin synthase (crystal form 1)==
 
<StructureSection load='2fr0' size='340' side='right'caption='[[2fr0]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
===The first ketoreductase of the erythromycin synthase (crystal form 1)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2fr0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FR0 FirstGlance]. <br>
{{ABSTRACT_PUBMED_16564177}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fr0 OCA], [https://pdbe.org/2fr0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fr0 RCSB], [https://www.ebi.ac.uk/pdbsum/2fr0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fr0 ProSAT]</span></td></tr>
[[2fr0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FR0 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/ERYA1_SACER ERYA1_SACER]
<ref group="xtra">PMID:016564177</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fr/2fr0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fr0 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharopolyspora erythraea]]
[[Category: Saccharopolyspora erythraea]]
[[Category: Keatinge-Clay, A T.]]
[[Category: Keatinge-Clay AT]]
[[Category: Stroud, R M.]]
[[Category: Stroud RM]]
[[Category: Oxidoreductase]]
[[Category: Short chain dehydrogenase/reductase]]

Latest revision as of 09:25, 14 February 2024

The first ketoreductase of the erythromycin synthase (crystal form 1)

2fr0, resolution 1.81Å

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