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[[Image:2pp0.png|left|200px]]


{{STRUCTURE_2pp0|  PDB=2pp0  |  SCENE=  }}
==Crystal structure of L-talarate/galactarate dehydratase from Salmonella typhimurium LT2==
 
<StructureSection load='2pp0' size='340' side='right'caption='[[2pp0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Crystal structure of L-talarate/galactarate dehydratase from Salmonella typhimurium LT2===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2pp0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PP0 FirstGlance]. <br>
{{ABSTRACT_PUBMED_17649980}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pp0 OCA], [https://pdbe.org/2pp0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pp0 RCSB], [https://www.ebi.ac.uk/pdbsum/2pp0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pp0 ProSAT]</span></td></tr>
[[2pp0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PP0 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/TAGAD_SALTY TAGAD_SALTY] Catalyzes the efficient dehydration of both L-talarate and galactarate to 5-keto-4-deoxy-D-glucarate. Also catalyzes the epimerization of L-talarate to galactarate; epimerization occurs in competition with dehydration. Is required for the utilization of L-talarate as a carbon source. Also functions in galactarate utilization. Is not active on other acid sugars.<ref>PMID:17649980</ref>
<ref group="xtra">PMID:017649980</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Almo, S C.]]
Check<jmol>
[[Category: Fedorov, A A.]]
  <jmolCheckbox>
[[Category: Fedorov, E V.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pp/2pp0_consurf.spt"</scriptWhenChecked>
[[Category: Gerlt, J A.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Yew, W S.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Enolase superfamily]]
  </jmolCheckbox>
[[Category: L-talarate/galactarate dehydratase]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pp0 ConSurf].
[[Category: Lyase]]
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Almo SC]]
[[Category: Fedorov AA]]
[[Category: Fedorov EV]]
[[Category: Gerlt JA]]
[[Category: Yew WS]]
Retrieved from "https://proteopedia.org/2pp0"