1wi0: Difference between revisions
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== | ==Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)== | ||
<StructureSection load='1wi0' size='340' side='right'caption='[[1wi0]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1wi0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WI0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WI0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wi0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wi0 OCA], [https://pdbe.org/1wi0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wi0 RCSB], [https://www.ebi.ac.uk/pdbsum/1wi0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wi0 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wi0 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MP2K5_MOUSE MP2K5_MOUSE] Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.<ref>PMID:10473620</ref> <ref>PMID:16507987</ref> | |||
==See Also== | |||
*[[Mitogen-activated protein kinase kinase 3D structures|Mitogen-activated protein kinase kinase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Hayashi F]] | |||
[[Category: Hayashi | [[Category: Inoue M]] | ||
[[Category: Inoue | [[Category: Kigawa T]] | ||
[[Category: Kigawa | [[Category: Koshiba S]] | ||
[[Category: Koshiba | [[Category: Tochio N]] | ||
[[Category: Yokoyama S]] | |||
[[Category: Tochio | [[Category: Yoneyama M]] | ||
[[Category: Yokoyama | |||
[[Category: Yoneyama | |||
Latest revision as of 09:28, 6 December 2023
Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)
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