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[[Image:2pkk.png|left|200px]]


{{STRUCTURE_2pkk| PDB=2pkk | SCENE= }}
==Crystal structure of M tuberculosis Adenosine Kinase complexed with 2-fluro adenosine==
<StructureSection load='2pkk' size='340' side='right'caption='[[2pkk]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2pkk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PKK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2FA:2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL'>2FA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pkk OCA], [https://pdbe.org/2pkk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pkk RCSB], [https://www.ebi.ac.uk/pdbsum/2pkk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pkk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ADOK_MYCTU ADOK_MYCTU] ATP dependent phosphorylation of adenosine to monophosphate derivatives (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pk/2pkk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pkk ConSurf].
<div style="clear:both"></div>


===Crystal structure of M tuberculosis Adenosine Kinase complexed with 2-fluro adenosine===
==See Also==
 
*[[Adenosine kinase 3D structures|Adenosine kinase 3D structures]]
{{ABSTRACT_PUBMED_17597075}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[2pkk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKK OCA].
 
==Reference==
<ref group="xtra">PMID:017597075</ref><references group="xtra"/>
[[Category: Adenosine kinase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Owen, J L.]]
[[Category: Palaninathan, S K.]]
[[Category: Reddy, M C.M.]]
[[Category: Sacchettini, J C.]]
[[Category: Shetty, N D.]]
[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: Watson, M D.]]
[[Category: 2 fluro adenosine]]
[[Category: Adenosine kinase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Structural genomic]]
[[Category: Owen JL]]
[[Category: Tb structural genomics consortium]]
[[Category: Palaninathan SK]]
[[Category: Tbsgc]]
[[Category: Reddy MCM]]
[[Category: Transferase]]
[[Category: Sacchettini JC]]
[[Category: Shetty ND]]
[[Category: Watson MD]]
Retrieved from "https://proteopedia.org/2pkk"