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[[Image:2krh.png|left|200px]]


{{STRUCTURE_2krh|  PDB=2krh  |  SCENE=  }}
==Structure of the C-terminal actin binding domain of ABRA==
 
<StructureSection load='2krh' size='340' side='right'caption='[[2krh]]' scene=''>
===Structure of the C-terminal actin binding domain of ABRA===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2krh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRH FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krh OCA], [https://pdbe.org/2krh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krh RCSB], [https://www.ebi.ac.uk/pdbsum/2krh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krh ProSAT]</span></td></tr>
[[2krh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRH OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/ABRA_RAT ABRA_RAT] Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.[UniProtKB:Q8BUZ1]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Fogl, C L.F.]]
[[Category: Fogl CLF]]
[[Category: Pfuhl, M.]]
[[Category: Pfuhl M]]
[[Category: Actin binding]]
[[Category: Actin-binding]]
[[Category: Actin-binding protein]]
[[Category: Cardiac]]
[[Category: Cytoskeleton]]
[[Category: Muscle]]
[[Category: Stress response]]

Latest revision as of 06:48, 1 May 2024

Structure of the C-terminal actin binding domain of ABRA

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