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[[Image:2fol.png|left|200px]]


{{STRUCTURE_2fol| PDB=2fol | SCENE= }}
==Crystal structure of human RAB1A in complex with GDP==
<StructureSection load='2fol' size='340' side='right'caption='[[2fol]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2fol]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FOL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.631&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fol OCA], [https://pdbe.org/2fol PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fol RCSB], [https://www.ebi.ac.uk/pdbsum/2fol PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fol ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RAB1A_HUMAN RAB1A_HUMAN] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/2fol_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fol ConSurf].
<div style="clear:both"></div>


===Crystal structure of human RAB1A in complex with GDP===
==See Also==
 
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
{{ABSTRACT_PUBMED_15608370}}
__TOC__
 
</StructureSection>
==About this Structure==
[[2fol]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOL OCA].
 
==Reference==
<ref group="xtra">PMID:015608370</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C.]]
[[Category: Large Structures]]
[[Category: Bochkarev, A.]]
[[Category: Arrowsmith C]]
[[Category: Edwards, A.]]
[[Category: Bochkarev A]]
[[Category: Park, H.]]
[[Category: Edwards A]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Park H]]
[[Category: Shen, L.]]
[[Category: Shen L]]
[[Category: Shen, Y.]]
[[Category: Shen Y]]
[[Category: Sundstrom, M.]]
[[Category: Sundstrom M]]
[[Category: Tempel, W.]]
[[Category: Tempel W]]
[[Category: Wang, J.]]
[[Category: Wang J]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: G-protein]]
[[Category: Gtp analogue]]
[[Category: Protein transport]]
[[Category: Rab]]
[[Category: Sgc]]
[[Category: Struct ural genomics consortium]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
Retrieved from "https://proteopedia.org/2fol"