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[[Image:2ky7.png|left|200px]]


{{STRUCTURE_2ky7|  PDB=2ky7  |  SCENE=  }}
==NMR Structural Studies on the Covalent DNA Binding of a Pyrrolobenzodiazepine-Naphthalimide Conjugate==
 
<StructureSection load='2ky7' size='340' side='right'caption='[[2ky7]]' scene=''>
===NMR Structural Studies on the Covalent DNA Binding of a Pyrrolobenzodiazepine-Naphthalimide Conjugate===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ky7]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KY7 FirstGlance]. <br>
{{ABSTRACT_PUBMED_20490406}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HY2:2-{2-[4-(3-{[(11AS)-7-METHOXY-5-OXO-2,3,5,10,11,11A-HEXAHYDRO-1H-PYRROLO[2,1-C][1,4]BENZODIAZEPIN-8-YL]OXY}PROPYL)PIPERAZIN-1-YL]ETHYL}-1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONE'>HY2</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ky7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ky7 OCA], [https://pdbe.org/2ky7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ky7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ky7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ky7 ProSAT]</span></td></tr>
[[2ky7]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KY7 OCA].  
</table>
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:020490406</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Kamal, A.]]
[[Category: Kamal A]]
[[Category: Langel, W.]]
[[Category: Langel W]]
[[Category: Rettig, M.]]
[[Category: Rettig M]]
[[Category: Weisz, K.]]
[[Category: Weisz K]]
[[Category: Dna]]
[[Category: Dna duplex]]
[[Category: Dna-drug complex]]
[[Category: Pbd-naphthalimide hybrid]]
[[Category: Pyrrolobenzodiazepine]]

Latest revision as of 06:50, 1 May 2024

NMR Structural Studies on the Covalent DNA Binding of a Pyrrolobenzodiazepine-Naphthalimide Conjugate

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