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[[Image:2fn4.png|left|200px]]


{{STRUCTURE_2fn4|  PDB=2fn4  |  SCENE=  }}
==The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state==
 
<StructureSection load='2fn4' size='340' side='right'caption='[[2fn4]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
===The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2fn4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FN4 FirstGlance]. <br>
{{ABSTRACT_PUBMED_016773572}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn4 OCA], [https://pdbe.org/2fn4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fn4 RCSB], [https://www.ebi.ac.uk/pdbsum/2fn4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fn4 ProSAT]</span></td></tr>
[[2fn4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN4 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/RRAS_HUMAN RRAS_HUMAN] Regulates the organization of the actin cytoskeleton.
<ref group="xtra">PMID:016773572</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/2fn4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fn4 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C.]]
[[Category: Large Structures]]
[[Category: Burgess, N.]]
[[Category: Arrowsmith C]]
[[Category: Debreczeni, J.]]
[[Category: Burgess N]]
[[Category: Delft, F von.]]
[[Category: Debreczeni J]]
[[Category: Doyle, D.]]
[[Category: Doyle D]]
[[Category: Edwards, A.]]
[[Category: Edwards A]]
[[Category: Elkins, J M.]]
[[Category: Elkins JM]]
[[Category: Gileadi, C.]]
[[Category: Gileadi C]]
[[Category: Papagrigoriou, E.]]
[[Category: Papagrigoriou E]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Salah E]]
[[Category: Salah, E.]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M.]]
[[Category: Turnbull AP]]
[[Category: Turnbull, A P.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Von Delft F]]
[[Category: Gdp/gtp binding]]
[[Category: Gtp hydrolysis]]
[[Category: Rra]]
[[Category: Sgc]]
[[Category: Signaling protein]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
Retrieved from "https://proteopedia.org/2fn4"