2i5e: Difference between revisions

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[[Image:2i5e.png|left|200px]]


{{STRUCTURE_2i5e|  PDB=2i5e  |  SCENE=  }}
==Crystal Structure of a Protein of Unknown Function MM2497 from Methanosarcina mazei Go1, Probable Nucleotidyltransferase==
 
<StructureSection load='2i5e' size='340' side='right'caption='[[2i5e]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===Crystal Structure of a Protein of Unknown Function MM2497 from Methanosarcina mazei Go1, Probable Nucleotidyltransferase===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2i5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_mazei_Go1 Methanosarcina mazei Go1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I5E FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
[[2i5e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I5E OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i5e OCA], [https://pdbe.org/2i5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i5e RCSB], [https://www.ebi.ac.uk/pdbsum/2i5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i5e ProSAT], [https://www.topsan.org/Proteins/MCSG/2i5e TOPSAN]</span></td></tr>
[[Category: Methanosarcina mazei]]
</table>
[[Category: Clancy, S.]]
== Function ==
[[Category: Du, J.]]
[https://www.uniprot.org/uniprot/COFC_METMA COFC_METMA] Guanylyltransferase that catalyzes the activation of 2-phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.[HAMAP-Rule:MF_02114]
[[Category: Joachimiak, A.]]
== Evolutionary Conservation ==
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Tan, K.]]
Check<jmol>
[[Category: Apc86122]]
  <jmolCheckbox>
[[Category: Hypothetic protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/2i5e_consurf.spt"</scriptWhenChecked>
[[Category: Mcsg]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Methanosarcina mazei go1]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Midwest center for structural genomic]]
  </jmolCheckbox>
[[Category: Protein structure initiative]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i5e ConSurf].
[[Category: Psi-2]]
<div style="clear:both"></div>
[[Category: Structural genomic]]
__TOC__
[[Category: Unknown function]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanosarcina mazei Go1]]
[[Category: Clancy S]]
[[Category: Du J]]
[[Category: Joachimiak A]]
[[Category: Tan K]]
Retrieved from "https://proteopedia.org/2i5e"