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[[Image:1wxj.gif|left|200px]]<br /><applet load="1wxj" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1wxj, resolution 1.70&Aring;" />
'''Crystal Structure Of Tryptophan Synthase A-Subunit with Indole-3-propanol phosphate From Thermus Thermophilus Hb8'''<br />


==About this Structure==
==Crystal Structure Of Tryptophan Synthase A-Subunit with Indole-3-propanol phosphate From Thermus Thermophilus Hb8==
1WXJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=IPL:'>IPL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXJ OCA].
<StructureSection load='1wxj' size='340' side='right'caption='[[1wxj]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
[[Category: Single protein]]
== Structural highlights ==
[[Category: Thermus thermophilus]]
<table><tr><td colspan='2'>[[1wxj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WXJ FirstGlance]. <br>
[[Category: Tryptophan synthase]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
[[Category: Asada, Y.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPL:INDOLE-3-PROPANOL+PHOSPHATE'>IPL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Kunishima, N.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxj OCA], [https://pdbe.org/1wxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wxj RCSB], [https://www.ebi.ac.uk/pdbsum/1wxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxj ProSAT], [https://www.topsan.org/Proteins/RSGI/1wxj TOPSAN]</span></td></tr>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
</table>
[[Category: IPL]]
== Function ==
[[Category: SO4]]
[https://www.uniprot.org/uniprot/TRPA_THET2 TRPA_THET2] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate (By similarity).
[[Category: riken structural genomics/proteomics initiative]]
== Evolutionary Conservation ==
[[Category: rsgi]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: structural genomics]]
Check<jmol>
[[Category: thermus thermophilus hb8]]
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wx/1wxj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wxj ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:49:05 2008''
==See Also==
*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus HB8]]
[[Category: Asada Y]]
[[Category: Kunishima N]]
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