2rr8: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "2rr8" [edit=sysop:move=sysop] |
No edit summary |
||
| (6 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Solution structure of calponin homology domain of IQGAP1== | |||
<StructureSection load='2rr8' size='340' side='right'caption='[[2rr8]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2rr8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RR8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RR8 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rr8 OCA], [https://pdbe.org/2rr8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rr8 RCSB], [https://www.ebi.ac.uk/pdbsum/2rr8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rr8 ProSAT]</span></td></tr> | |||
== | </table> | ||
[[2rr8]] is a 1 chain structure with sequence from [ | == Function == | ||
[https://www.uniprot.org/uniprot/IQGA1_HUMAN IQGA1_HUMAN] Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.<ref>PMID:15695813</ref> | |||
== | == Evolutionary Conservation == | ||
<ref | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rr/2rr8_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rr8 ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Nishida | [[Category: Large Structures]] | ||
[[Category: Ogino | [[Category: Nishida N]] | ||
[[Category: Shimada | [[Category: Ogino S]] | ||
[[Category: Umemoto | [[Category: Shimada I]] | ||
[[Category: Umemoto R]] | |||
Latest revision as of 10:02, 14 June 2023
Solution structure of calponin homology domain of IQGAP1
| ||||||||||||
